Related Experiment Video
Updated: Mar 12, 2026

3D Imaging of PDL Collagen Fibers during Orthodontic Tooth Movement in Mandibular Murine Model
Published on: April 15, 2021
[TMJ and orthodontics, "past, present and future"]
A Manière-Ezvan1, A Oueiss1, F Busson1
1UFR d'odontologie, 24, avenue des Diables-Bleus, 06357 Nice cedex 4, France; Pôle odontologie du CHU de Nice, hôpital St-Roch, rue Devoluy, 06000 Nice, France.
The temporomandibular joint (TMJ) plays a crucial role in mandibular growth, influenced by mechanical stimulation and function from an early age. Prevention and early intervention through behavioral counseling and orthodontic management are key for healthy TMJ development and preventing temporomandibular dysfunction (TMD).
Area of Science:
- Orthodontics and Dental Development
- Temporomandibular Joint (TMJ) Biology
- Craniofacial Growth and Function
Background:
- Historically, the temporomandibular joint (ATM) was primarily linked to mandibular condyle growth, with rodent studies demonstrating condylar cartilage's role in response to orthopedic appliances.
- Class II malocclusion treatments aimed at mandibular growth have yielded inconclusive results, especially with the advent of orthognathic surgery.
Framework:
- Current understanding emphasizes mechanical stimulation and function as primary shapers of the ATM during development, starting from infancy.
- Prevention of developmental dysplasias involves early behavioral guidance, encouraging mandibular propulsion through breastfeeding and a hard diet promoting alternating unilateral chewing.
Implementation:
- Addressing temporomandibular dysfunction (TMD) requires understanding its specific manifestations, particularly in adolescents, and its interaction with orthodontic treatments.
- Effective therapeutic strategies include behavioral counseling for susceptible individuals (e.g., hyperdivergent females with small condyles), precise condylar position control, and post-orthodontic occlusal adjustments.
Implications:
- Future orthodontic approaches for the TMJ hinge on robust prevention, early screening, and advanced knowledge of TMJ and TMD.
- Orthodontists can now identify at-risk patients, modify treatment plans accordingly, or ensure perfect treatment completion for optimal TMJ health.
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