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Updated: May 10, 2026

Optogenetic Activation of Afferent Pathways in Brain Slices and Modulation of Responses by Volatile Anesthetics
Published on: July 23, 2020
[Propofol up2date. Part 1: history and pharmacological characteristics]
Stefan Bushuven1, Daniel Heise
1Instituts für Anästhesiologie,Intensivmedizin, Notfallmedizin und Schmerztherapie am Hegau-Bodensee-Klinikum Singen. stefan.bushuven@hbh-kliniken.de
Abstract:
Propofol is a common hypnotic agent in anaesthesiology and intensive care medicine and for procedural sedation as well. Despite the intensive usage the full potential, pharmacokinetic and -dynamic abilities, interactions and side effects of the substance may not be realized by all providers. Additionally there is dispute and unwarranted myth about the substance. Propofol is a highly potent hypnotic with a wide range of (un)desired effects. This article is reviewing the diversity of the substance in clinical practice.
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