Related Experiment Video
Updated: May 10, 2026
13:53
The Helsinki Rat Microsurgical Sidewall Aneurysm Model
Published on: October 12, 2014
A predictive model of outcomes during cerebral aneurysm coiling
Kimon Bekelis1, Symeon Missios, Todd A Mackenzie
1Section of Neurosurgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.
Journal of Neurointerventional Surgery
|July 6, 2013
Summary
A new predictive model helps anticipate negative outcomes after cerebral aneurysm coiling (CACo). This tool aids clinicians in tailoring treatments and improving patient care for cerebral aneurysms.
Area of Science:
- Neurosurgery
- Interventional Neurology
- Health Services Research
Background:
- Benchmarking complications is crucial for accountable care in neurosurgery.
- Developing predictive models for negative outcomes in cerebral aneurysm coiling (CACo) is essential.
Purpose of the Study:
- To create a predictive model for negative outcomes in patients undergoing cerebral aneurysm coiling.
- To identify risk factors associated with postoperative complications.
Main Methods:
- Retrospective cohort study of 10,607 patients undergoing CACo (2005-2009) from the Nationwide Inpatient Sample database.
- Development and validation of a predictive model using individual patient characteristics.
- Multivariate analysis to identify independent risk factors for various complications.
Main Results:
- The study analyzed outcomes for both unruptured (57.1%) and ruptured (42.9%) aneurysms.
- Identified significant inpatient postoperative risks including death, unfavorable discharge, stroke, and specific complications.
- The developed model demonstrated good predictive discrimination, validated by the area under the receiver operating characteristic curve.
Conclusions:
- The validated model can predict the incidence of postoperative complications following cerebral aneurysm coiling.
- This predictive tool can assist in personalizing treatment strategies for cerebral aneurysms.
Related Concept Videos
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
01:26Aneurysm III: Interprofessional Care
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
01:30Aneurysm I: Introduction
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
01:22Aneurysm IV: Nursing Management
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...