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Related Experiment Video

Updated: May 10, 2026

3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii

3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii

Published on: December 9, 2014

Toxoplasmosis.

Sandra K Halonen¹, Louis M Weiss

¹Department of Microbiology, Montana State University, Bozeman, MT, USA.

Handbook of Clinical Neurology

|July 9, 2013

Summary

This summary is machine-generated.

Toxoplasma gondii is a common parasite affecting one-third of the world population. This review covers its biology, transmission, and potential links to neurological and neuropsychiatric disorders.

Keywords:

Toxoplasma bradyzoite cerebral infection chorioretinitis encephalitis immune response immunodeficiency latency pyrimethamine seizure tachyzoite zoonosis

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Toxoplasma gondii Cyst Wall Formation in Activated Bone Marrow-derived Macrophages and Bradyzoite Conditions

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Published on: August 12, 2010

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Last Updated: May 10, 2026

3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii

3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii

Published on: December 9, 2014

Toxoplasma gondii Cyst Wall Formation in Activated Bone Marrow-derived Macrophages and Bradyzoite Conditions

Toxoplasma gondii Cyst Wall Formation in Activated Bone Marrow-derived Macrophages and Bradyzoite Conditions

Published on: August 12, 2010

Area of Science:

Parasitology
Neuroscience
Infectious Diseases

Background:

Toxoplasma gondii is an Apicomplexan protozoan pathogen.
Infection can cause severe neurological issues in congenital cases and encephalitis in immunocompromised individuals.
Asymptomatic infections in immunocompetent individuals may influence behavior and physiology.

Purpose of the Study:

To review the biology of Toxoplasma gondii infection.
To discuss transmission, epidemiology, and parasite strains.
To explore clinical outcomes and associations with neuropsychiatric disorders.

Main Methods:

Literature review of Toxoplasma gondii biology.
Analysis of transmission routes and life cycle stages.
Examination of epidemiological data and host immune responses.

Main Results:

T. gondii has a complex life cycle involving cats and intermediate hosts.
Type I strains are associated with increased pathogenicity in humans.
Congenital infections can lead to chorioretinitis and encephalitis.

Conclusions:

T. gondii infection is widespread and presents diverse clinical outcomes.
Further research is needed to understand the link between asymptomatic toxoplasmosis and neuropsychiatric conditions like schizophrenia.