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Updated: May 10, 2026

Lipidomics and Transcriptomics in Neurological Diseases

Lipidomics and Transcriptomics in Neurological Diseases

Published on: March 18, 2022

Nutritional disorders in tropical neurology.

Gustavo C Román¹

¹Department of Neurology, Weill Cornell Medical College and Nantz National Alzheimer Center, Methodist Neurological Institute, Houston, TX, USA.

Handbook of Clinical Neurology

|July 9, 2013

Summary

Tropical populations face severe malnutrition due to limited food access and poor sanitation, leading to health issues like developmental delays and infections. Addressing nutritional deficiencies, such as iodine, is crucial for improving health outcomes in these regions.

Keywords:

Cuban epidemic neuropathy Hunger Wernicke–Korsakoff alcohol alcoholism beriberi burning feet cobalamin folic acid homocysteine iodine iron kwashiorkor malnutrition marasmus micronutrient deficiencies myeloneuropathy niacin nicotinamide night blindness nutritional amblyopia nutritional brain atrophy nutritional myelopathy nutritional neuropathy omega-3 fatty acids optic neuropathy pantothenic acid pellagra polyneuropathy prisoners of war psychomotor retardation pyridoxine deficiency riboflavin selenium subacute combined degeneration thiamin tobacco-alcohol amblyopia vitamin A vitamin B(12)vitamin B-complex vitamin D vitamin E vitamins α-tocopherol

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Last Updated: May 10, 2026

Lipidomics and Transcriptomics in Neurological Diseases

Lipidomics and Transcriptomics in Neurological Diseases

Published on: March 18, 2022

Area of Science:

Global Health
Nutritional Science
Tropical Medicine

Background:

Tropical regions house a large population with disproportionately low food consumption and economic contribution.
Inadequate access to clean water and sanitation exacerbates health issues, increasing malnutrition prevalence.
Iodine deficiency affects a significant portion of the global population, risking cognitive impairments.

Purpose of the Study:

To highlight the critical nutritional challenges and health disparities in tropical populations.
To underscore the impact of deficiencies in macronutrients and micronutrients on tropical health.
To identify key nutritional syndromes prevalent in the tropics.

Main Methods:

Analysis of global population distribution, food production, and economic data.
Review of health outcomes associated with poor nutrition, sanitation, and water quality.
Identification and categorization of major nutritional syndromes and deficiencies.

Main Results:

Tropical regions face significant food insecurity, contributing to poor health indicators like low life expectancy and high infant mortality.
Water-borne diseases and malabsorption are widespread due to poor sanitation, worsening malnutrition.
Prevalence of protein-energy malnutrition, nutritional neuropathies, and deficiencies in iodine, iron, zinc, and selenium are significant concerns.

Conclusions:

Urgent interventions are needed to improve food security, sanitation, and access to clean water in the tropics.
Addressing specific micronutrient deficiencies, particularly iodine, is vital for preventing developmental disorders.
Comprehensive strategies are required to combat the multifaceted issue of malnutrition in tropical regions.