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[Hypoactive sexual desire and testosterone deficiency in men]
Summary
Testosterone stimulates sexual desire, especially in men with hypogonadism. Testosterone replacement therapy can restore libido when testosterone levels are low and other causes are excluded.
Area of Science:
- Endocrinology
- Andrology
- Sexual Medicine
Context:
- The relationship between testosterone and sexual desire is complex, particularly in aging males.
- Aging men may experience late-onset hypogonadism, affecting sexual desire.
- Multiple factors, including health and psychological elements, influence sexual desire alongside testosterone levels.
Purpose:
- To review the literature on the relationship between testosterone and sexual desire in men.
- To clarify the role of testosterone in stimulating sexual desire.
- To examine the impact of testosterone replacement therapy (TRT) on sexual desire.
Summary:
- Testosterone is a physiological stimulator of sexual desire; complete hypogonadism leads to very low libido, which TRT can restore.
- Epidemiological studies show a statistically significant but less strict relationship due to interacting factors affecting both desire and testosterone.
- In aging males, factors beyond hypogonadism, such as health, partnership, socioeconomic status, psychological factors, and erectile dysfunction, must be considered.
Impact:
- Decreased sexual desire can be a symptom of late-onset hypogonadism.
- TRT is most effective when testosterone is low and other causes of impaired sexual desire are absent.
- Current evidence suggests TRT does not increase the risk of prostate cancer or benign prostatic hyperplasia.
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