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Related Experiment Video

Updated: May 10, 2026

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease
02:21

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease

Published on: March 15, 2024

[Lapeyronie's disease].

L Ferretti1, A Faix, S Droupy

  • 1CHU de Bordeaux, Pellegrin, place Amélie-Raba-Léon, 33076 Bordeaux cedex, France.

Progres En Urologie : Journal De L'Association Francaise D'Urologie Et De La Societe Francaise D'Urologie
|July 9, 2013
PubMed
Summary
This summary is machine-generated.

Lapeyronie's disease, also known as Peyronie's disease, affects 3.4-9% of men. Current medical treatments are ineffective, and surgery is recommended for stabilized penile curvature, with implants for severe cases combined with erectile dysfunction.

Keywords:
Chirurgie du pénisCourbure du pénisDysfonction érectileErectile dysfunctionImplants péniensLapeyronie's diseaseMaladie de LapeyronieMedical penile surgeryNesbitPenile curvaturePenile implantPenile plicatureTGF-βYachia

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Urethroplasty with Pedicled Tunica Vaginalis for the Treatment of Long-segment Anterior Urethral Stricture Caused by Lichen Sclerosus of Glans Penis

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Last Updated: May 10, 2026

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease
02:21

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease

Published on: March 15, 2024

Urethroplasty with Pedicled Tunica Vaginalis for the Treatment of Long-segment Anterior Urethral Stricture Caused by Lichen Sclerosus of Glans Penis
03:55

Urethroplasty with Pedicled Tunica Vaginalis for the Treatment of Long-segment Anterior Urethral Stricture Caused by Lichen Sclerosus of Glans Penis

Published on: October 18, 2024

Area of Science:

  • Urology
  • Andrology
  • Medical Research

Context:

  • Lapeyronie's disease (PD) affects a significant portion of the male population (3.4-9%).
  • Understanding PD pathophysiology, natural history, and treatment outcomes is crucial for patient management.
  • Existing literature on PD has limited high-level evidence, with most studies at level 2b or 3.

Purpose:

  • To review the existing literature on Lapeyronie's disease (PD).
  • To synthesize current knowledge regarding PD pathophysiology, natural history, and treatment efficacy.
  • To provide guidance for clinical decision-making in managing PD patients.

Summary:

  • A literature review of 75 articles (1940-2012) was conducted using keywords related to Lapeyronie's disease and its treatments.
  • The pathophysiology of PD remains controversial.
  • Medical treatments for PD have demonstrated ineffectiveness.
  • Surgical intervention is advised for stabilized penile curvature, tailored to penile size, angle, and erectile function.
  • Penile implants are indicated for patients with severe curvature and coexisting erectile dysfunction.

Impact:

  • Highlights the controversial nature of PD pathophysiology.
  • Underscores the limited efficacy of current medical treatments for PD.
  • Provides evidence-based recommendations for surgical management of PD, including penile implants for specific cases.
  • Aims to improve patient care by guiding treatment decisions based on disease characteristics and patient factors.