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Extensive calcinosis cutis with systemic lupus erythematosus
M J Rothe1, J M Grant-Kels, N F Rothfield
1Division of Dermatology, University of Connecticut Health Center, Farmington 06032.
Archives of Dermatology
|August 1, 1990
Summary
Extensive calcinosis cutis, a skin condition, is rarely seen in systemic lupus erythematosus (SLE). This study details three SLE patients with this rare manifestation, identifying shared characteristics with other reported cases.
Area of Science:
- Rheumatology
- Dermatology
- Internal Medicine
Background:
- Calcinosis cutis is a known complication in connective tissue diseases like dermatomyositis and scleroderma.
- Its occurrence in systemic lupus erythematosus (SLE) is infrequently documented, making it a rare clinical finding.
Observation:
- This report describes three patients with established systemic lupus erythematosus (SLE) who developed extensive calcinosis cutis.
- The patients presented with significant cutaneous calcification, a manifestation not typically associated with SLE.
Findings:
- The study analyzes shared characteristics among these three patients and 23 previously reported cases of calcinosis cutis in SLE.
- Identifying common features may help in understanding the pathogenesis and clinical spectrum of this rare association.
Implications:
- This research highlights the importance of considering calcinosis cutis in the differential diagnosis of cutaneous manifestations in SLE patients.
- Further investigation into the specific factors contributing to calcinosis cutis in SLE could lead to improved patient management and targeted therapies.