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Functional hemispheric lateralization for language in patients with schizophrenia

Mathieu Alary1, Nicolas Delcroix, Elise Leroux

  • 1CNRS, UMR 6301, ISTS team. GIP CYCERON, F-14074 Caen, France.

Schizophrenia Research
|July 9, 2013
PubMed
Summary

Patients with schizophrenia show reduced leftward brain lateralization for language. Unlike healthy individuals, this functional difference in schizophrenia patients is not linked to grey matter volume asymmetry.

Keywords:
AHRSAuditory Hallucinations Rating ScaleBOLDCSCSiDSM IVEPIETFAFLIFOVFWEFWHMFunctional hemispheric lateralizationFunctional magnetic resonance imagingGMGVAIGrey matter volume asymmetryHRFITLHLanguageMINIMNIMini International Neuropsychiatric InterviewMontreal Neurological InstitutePANSSPositive And Negative Syndrome ScaleRHROIRTSDSPM5Schizophreniablood oxygen level dependentcomprehension scoredegree of freedomdiagnostic and statistical manual of mental disorders 4th editiondofecho planar imagingecho timefMRIfamily wise errorfield of viewflip anglefull width at half maximumfunctional laterality indexfunctional magnetic resonance imaginggrey mattergrey matter volume asymmetry indexhemodynamic response functionindividual comprehension scoreinversion timeleft hemispherenn-CSnormalized comprehension scoresnumberregions of interestrepetition timeright hemispherestandard deviationstatistical parametric mapping 5

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