Acetylation of α-tubulin on Lys40 is a widespread post-translational modification in angiosperms
Umihito Nakagawa1, Daisuke Suzuki, Mai Ishikawa
1Department of Bioscience, Nagahama Institute of Bio-Science and Technology, Nagahama, Shiga, Japan.
Abstract:
Acetylation of α-tubulin on Lys(40) is thought to be a modification that regulates the dynamic instability of microtubules, but little is known about the occurrence of α-tubulin acetylation in plants. Here we report on a growth stage-dependent change in levels of α-tubulin acetylation and the organ distribution of acetylated α-tubulin in Arabidopsis thaliana plants. Widespread occurrence of α-tubulin acetylation in the leaves of 15 species (20 cultivars) of angiosperms was also confirmed. Our data indicate that acetylated α-tubulin is widespread in many angiosperms, but levels can differ, sometimes considerably, among different organs and developmental stages.
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