Related Experiment Video

Updated: Aug 12, 2026

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment
07:45

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment

Published on: November 6, 2018

Incidence of hypertrophic scarring in burn-injured children

E D Spurr1, P G Shakespeare

  • 1Laing Laboratory for Burn Injury Investigation, Odstock Hospital, Salisbury, UK.

Burns : Journal of the International Society for Burn Injuries
|June 1, 1990
PubMed

Insights

Hypertrophic scarring occurred in at least 50% of young children with burns in both 1968 and 1984. Clinical practice changes did not seem to affect the incidence of these scars in pediatric burn patients.

Area of Science:

  • Pediatric burn care
  • Dermatology
  • Wound healing

Background:

  • Hypertrophic scarring is a common complication following burns, particularly in pediatric patients.
  • Understanding the incidence and potential influencing factors of hypertrophic scarring is crucial for improving patient outcomes.

Purpose of the Study:

  • To investigate the occurrence of hypertrophic scarring in children under 5 years old who sustained burn injuries.
  • To compare the incidence of hypertrophic scarring in two different time periods (1968 and 1984) to identify potential trends or influences.

Main Methods:

  • Retrospective analysis of patient records from the Wessex Regional Burns Unit.
  • Inclusion criteria: children under 5 years of age admitted with burn injuries in 1968 and 1984.
  • Assessment of hypertrophic scarring incidence based on medical records.

Main Results:

  • The pattern and nature of burn injuries were consistent between 1968 and 1984.
  • The incidence of hypertrophic scarring was at least 50% in both study years.
  • No significant influence of changes in clinical practice on hypertrophic scarring occurrence was observed.

Conclusions:

  • Hypertrophic scarring remains a significant issue in pediatric burn patients, with a high incidence observed over a 16-year period.
  • The findings suggest that factors beyond clinical practice may play a substantial role in the development of hypertrophic scarring in young children.
  • Further research is warranted to explore other contributing factors and develop more effective preventative or treatment strategies.

More Related Videos

In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding08:20

In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding

Published on: May 1, 2020

A Mouse Model of Mechanotransduction-driven, Human-like Hypertrophic Scarring05:54

A Mouse Model of Mechanotransduction-driven, Human-like Hypertrophic Scarring

Published on: November 29, 2024

Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...