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Updated: May 9, 2026

Pattern-based Search of Epigenomic Data Using GeNemo
Published on: October 8, 2017
Environmental epigenetics: from novelty to scientific discipline
Heather H Burris1, Andrea A Baccarelli
1Department of Neonatology, Beth Israel Deaconess Medical Center & Division of Newborn Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Environmental epigenetics research is growing but still small. Future success requires focusing on tissue specificity, interventions, collaboration, and broader mechanisms beyond DNA methylation.
Area of Science:
- Environmental epigenetics
- Molecular biology
- Public health
Background:
- Epigenetic phenomena have seen a surge in research over the last two decades.
- Environmental epigenetics is a smaller, yet growing, subfield compared to areas like cancer epigenetics.
- Significant investment from the National Institute of Environmental Health Sciences underscores the potential of this field.
Purpose of the Study:
- To delineate the current landscape of environmental epigenetics research.
- To articulate a forward-looking strategy for the advancement of the field.
- To highlight the potential for improved health outcomes through epigenetic interventions.
Main Methods:
- Review of current epigenetic publications and funding allocations.
- Analysis of the scope and focus of existing environmental epigenetics studies.
- Identification of key areas for future research and development.
Main Results:
- Environmental epigenetic studies constitute less than 5% of all epigenetic publications.
- Despite low publication numbers, substantial funding is directed towards environmental epigenetics research.
- The field holds promise for understanding gene-environment interactions and health.
Conclusions:
- Advancing environmental epigenetics necessitates attention to tissue specificity and focused interventional studies.
- Collaboration among research cohorts and integration of environmental exposures into large-scale epigenomic studies are crucial.
- A comprehensive understanding of epigenetic mechanisms beyond DNA methylation and histone modifications is vital for realizing the field's potential to benefit future generations.
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