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Related Concept Videos

The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...

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Related Experiment Video

Updated: May 9, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
07:01

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

Published on: April 17, 2013

[Trichoblastic carcinoma].

A A Oufkir1, K Znati, D Kamal

  • 1Service d'oto-rhino-laryngologie et chirurgie plastique, CHU Hassan II, Fez, Morocco. ayaoufkir@gmail.com

Revue De Stomatologie, De Chirurgie Maxillo-Faciale Et De Chirurgie Orale
|July 11, 2013
PubMed
Summary
This summary is machine-generated.

Trichoblastic carcinoma, a rare eyelid tumor, can present atypically with extensive subcutaneous growth. Prompt surgical excision and radiotherapy led to a favorable outcome in this unique case.

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Last Updated: May 9, 2026

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Area of Science:

  • Dermatology
  • Oncology

Background:

  • Trichoblastic carcinoma is a rare malignant adnexal tumor.
  • Diagnosis is confirmed histologically due to non-specific presentation.

Observation:

  • A 56-year-old patient developed trichoblastic carcinoma on the eyelid and eyebrow, 7 years post-incomplete excision.
  • The tumor exhibited significant subcutaneous extension beyond visible skin margins.

Findings:

  • Broad surgical excision followed by radiotherapy was performed.
  • No local recurrence or metastasis was observed at 20 months post-treatment.

Implications:

  • This case highlights an atypical presentation of trichoblastic carcinoma.
  • Effective therapeutic management for rare adnexal tumors is discussed.