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Updated: May 9, 2026

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Preparation, Purification, and Use of Fatty Acid-containing Liposomes
Published on: February 9, 2018
Functionalized liposome purification via Liposome Extruder Purification (LEP)
Nathan J Alves1, William Cusick, Jared F Stefanick
1Department of Chemical and Biomolecular Engineering, University of Notre Dame, 165 Fitzpatrick Hall, Notre Dame, IN 46556-5637, USA.
The Analyst
|July 11, 2013
Abstract:
Liposome Extruder Purification (LEP) allows for the rapid purification of diverse liposome formulations using the same extrusion apparatus employed during liposome formation. The LEP process provides a means for purifying functionalized liposomes from non-conjugated drug or protein contaminants with >93% liposome recovery and >93% contaminant removal in a single step.

