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Updated: May 9, 2026

A Mouse Model of Vascularized Heterotopic Spleen Transplantation for Studying Spleen Cell Biology and Transplant Immunity
08:04

A Mouse Model of Vascularized Heterotopic Spleen Transplantation for Studying Spleen Cell Biology and Transplant Immunity

Published on: June 11, 2019

Can the spleen be divided into two functional parts?

Hongchi Jiang1, Lianxin Liu, Jizhou Wang

  • 1Key Laboratory of Hepatosplenic Surgery, Department of General Surgery, The First Affiliated Hospital, Harbin Medical University, Harbin, China.

Journal of Clinical Gastroenterology
|July 12, 2013
PubMed

Solid evidence has revealed unsuspected functions of the spleen. Asplenic or hyposplenic patients bear an increased susceptibility to overwhelming postsplenectomy infection. We, for the first time, performed the split splenic transplantation to redress hemophilia A. We also resected the middle part of the spleen completely and anatomically for the first time. Our findings illustrate that the spleen can be divided into 2 functional parts, and may shed a new light on the understanding and practice in splenic surgery.

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