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CT-guided thoracic biopsy: evaluating diagnostic yield and complications
Stanley E K Loh1, Donald D F Wu, Sudhakar K Venkatesh
1Department of Diagnostic Imaging, National University Hospital, Singapore.
Annals of the Academy of Medicine, Singapore
|July 12, 2013
Summary
CT-guided thoracic biopsy is a safe and effective procedure with high diagnostic accuracy for thoracic lesions. Key factors influencing complications like pneumothorax include traversed lung length and lesion size.
Area of Science:
- Thoracic imaging and interventions
- Interventional radiology procedures
- Pulmonary diagnostics
Background:
- CT-guided thoracic biopsy is a crucial diagnostic tool.
- Evaluating its efficacy and safety is essential for clinical practice.
Purpose of the Study:
- To retrospectively assess the diagnostic yield, accuracy, and complication rates of CT-guided thoracic biopsies.
- To identify factors correlating with procedural complications.
Main Methods:
- Retrospective analysis of 399 CT-guided thoracic biopsies in 384 patients.
- Evaluation of diagnostic yield, accuracy, and complications (pneumothorax, haemothorax, haemoptysis).
- Correlation analysis of patient and procedure factors with complications; comparison of fine needle aspiration (FNA) versus core biopsy groups.
Main Results:
- High diagnostic yield (91.9%) and accuracy for malignancy (96.8%).
- Pneumothorax occurred in 34.8% (3.0% required drainage); haemoptysis in 3.2%.
- Pneumothorax and haemoptysis associated with traversed lung-length and smaller lesion size.
Conclusions:
- CT-guided thoracic biopsy is a safe procedure with high diagnostic yield and low significant complication risk.
- Traversed lung-length and smaller lesion size are significant predictors for pneumothorax and haemoptysis.
- No significant difference in yield or complications between FNA and core biopsy techniques.
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