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Primary pleural angiosarcoma in a 63-year-old gentleman.
Ahmed Abu-Zaid1, Shamayel Mohammed
1College of Medicine, Alfaisal University, P.O. Box 50927, Riyadh 11533, Saudi Arabia.
Case Reports in Pulmonology
|July 12, 2013
Summary
Primary pleural angiosarcoma, a rare cancer, was diagnosed in a 63-year-old man presenting with chest pain and dyspnea. Despite treatment, the patient unfortunately passed away. This case highlights the rarity of this condition.
Area of Science:
- Oncology
- Pathology
- Radiology
Background:
- Primary pleural angiosarcomas are exceptionally rare, with fewer than 50 cases reported by 2010.
- This highlights the diagnostic and therapeutic challenges posed by these rare tumors.
Purpose of the Study:
- To report a rare case of primary pleural epithelioid angiosarcoma.
- To discuss the diagnostic modalities and histopathological features.
- To review the existing literature on pleural angiosarcoma.
Main Methods:
- Case presentation of a 63-year-old male with chest pain, dyspnea, and hemoptysis.
- Diagnostic imaging included chest X-ray, CT scan, and PET/CT scan.
- Histopathological and immunohistochemical analysis of CT-guided biopsy specimens.
Main Results:
- Imaging revealed bilateral pleural effusion and diaphragmatic pleural masses.
- Biopsy confirmed epithelioid angiosarcoma with positive markers (vimentin, CD31, CD68, Fli-1).
- The patient experienced a fatal outcome due to cardiac arrest post-discharge.
Conclusions:
- Epithelioid angiosarcoma of the pleura is a rare and aggressive malignancy.
- Multimodality imaging and immunohistochemistry are crucial for diagnosis.
- Despite aggressive management, outcomes remain poor for primary pleural angiosarcoma.
