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Updated: May 9, 2026
08:49
Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
Published on: May 11, 2018
Clinical differences between continuous flow ventricular assist devices: a comparison between HeartMate II and
Spencer D Lalonde1, Ana C Alba, Alanna Rigobon
1Heart Failure/Transplant Program, Peter Munk Cardiac Centre, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Journal of Cardiac Surgery
|July 13, 2013
Summary
The HeartWare Ventricular Assist Device (HVAD) showed higher rates of gastrointestinal bleeding and stroke compared to the HeartMate II (HMII). Further management refinements are needed to reduce these complications in HVAD patients.
Area of Science:
- Cardiology
- Medical Devices
- Surgical Technology
Background:
- The HeartWare Ventricular Assist Device (HVAD) is a newer centrifugal-flow VAD.
- The HeartMate II (HMII) is an established axial-flow VAD.
- Limited comparative studies exist for newer VAD generations.
Purpose of the Study:
- To compare clinical outcomes between the HVAD and HMII devices.
- To evaluate the safety and efficacy of HVAD versus HMII in LVAD recipients.
Main Methods:
- Prospective data collection of perioperative and follow-up information.
- Analysis of 46 LVAD recipients (13 HVAD, 33 HMII) implanted between 2006-2012.
- Comparison of baseline demographics, perioperative, and postoperative outcomes.
Main Results:
- No significant differences in survival, bleeding, renal, liver dysfunction, or infection rates.
- HVAD group showed significantly higher incidence of gastrointestinal bleeding (31% vs 0%) and stroke (44% vs 10% at one year).
- Hemorrhagic strokes were more frequent in the HVAD group (p=0.06).
Conclusions:
- While overall device complications were similar, HVAD is associated with increased risk of stroke and GI bleeding.
- Patient management strategies may need refinement to mitigate these specific HVAD complications.
- Further research is warranted to optimize HVAD patient care.
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