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Updated: May 9, 2026

Generation of Monoclonal Cultures from Wolbachia-infected Drosophila melanogaster JW18 Cell Line
Published on: June 27, 2025
Wolbachia: Can we save lives with a great pandemic?
Daniel LePage1, Seth R Bordenstein
1Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA. daniel.lepage@vanderbilt.edu
Abstract:
Wolbachia pipientis is the most common bacterial infection in the animal world and wields a vast influence on invertebrate reproduction, sex determination, speciation, and behavior worldwide. These avenues of research have made seminal gains, including the latest use of Wolbachia to alter mosquito populations and a strengthened focus on using anti-Wolbachia therapies against filarial nematode infections. This work is further bolstered by a more refined knowledge of Wolbachia biology spanning mechanisms to relevance. Here we tally the most up-to-date knowledge in the field and review the immense implications that this global infection has for the basic and applied life sciences.
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