CYP2B6 pharmacogenetics-based in vitro-in vivo extrapolation of efavirenz clearance by physiologically based

Cong Xu1, Sara K Quinney, Yingying Guo

  • 1Division of Clinical Pharmacology (C.X., Z.D.), Department of Obstetrics and Gynecology (S.K.Q.) and Center for Computational Biology and Bioinformatics (L.L.), Indiana University School of Medicine, Indianapolis, Indiana; and Department of Drug Disposition, Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, Indiana (Y.G., S.D.H.).

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