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Related Concept Videos

Primary Lymphoid Organs01:16

Primary Lymphoid Organs

Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Liver Histology01:27

Liver Histology

The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...

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Updated: May 9, 2026

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy
04:41

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Published on: March 10, 2023

Primary liver lymphoma.

S Khalid1, S Zaheer, M Khalid

  • 1Department of Radiodiagnosis, Jawaharlal Nehru Medical College, AMU, Aligarh, India. saif2k2@gmail.com

JBR-BTR : Organe De La Societe Royale Belge De Radiologie (SRBR) = Orgaan Van De Koninklijke Belgische Vereniging Voor Radiologie (KBVR)
|July 16, 2013
PubMed
Summary
This summary is machine-generated.

Primary liver lymphoma is rare but should be considered in patients with liver lesions. This case highlights its potential for late-stage central nervous system and vertebral dissemination despite initial chemotherapy response.

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Area of Science:

  • Oncology
  • Hepatology
  • Hematology

Background:

  • Liver involvement is common in systemic lymphoma.
  • Primary liver lymphoma (PLL) is an exceptionally rare condition.
  • Differentiating PLL from secondary liver involvement is diagnostically challenging.

Observation:

  • A middle-aged male presented with symptoms suggestive of liver disease.
  • Extensive workup confirmed a diagnosis of primary non-Hodgkin's liver lymphoma.
  • Initial response to chemotherapy was observed.

Findings:

  • The patient experienced relapse 15 months post-treatment.
  • Relapse manifested as dissemination to the central nervous system and vertebrae.
  • No evidence of vascular invasion, lymphadenopathy, or spleen involvement was noted at diagnosis.

Implications:

  • PLL should be included in the differential diagnosis for unexplained liver space-occupying lesions.
  • Vigilance for late-stage dissemination is crucial, even after initial treatment response.
  • Further research into the unique behavior and treatment of PLL is warranted.