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Updated: May 9, 2026
07:37
Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
[Bone mineral density disminution post Roux-Y bypass surgery]
Karin Papapietro1, Teresa Massardo, Andrea Riffo
1Departamento Cirugía, Hospital Clínico Universidad de Chile, Chile.
Nutricion Hospitalaria
|July 16, 2013
Summary
Bariatric surgery patients, even with calcium and vitamin D, experience bone loss. Regular bone density checks are vital for managing osteopenia and osteoporosis post-surgery.
Area of Science:
- Endocrinology
- Metabolic Surgery
- Bone Health
Context:
- Bariatric surgery, specifically Roux-en-Y gastric bypass (RYGB), is associated with significant metabolic complications, including bone mass loss.
- Standard calcium and vitamin D supplementation is often prescribed post-RYGB.
- Assessing long-term bone mineral density (BMD) changes is crucial for patient management.
Purpose:
- To evaluate bone mineral density (BMD) in patients following Roux-en-Y gastric bypass (RYGB).
- To determine the prevalence of osteopenia and osteoporosis in diverse age groups and genders post-RYGB.
- To assess the effectiveness of standard calcium and vitamin D supplementation in preventing bone loss.
Summary:
- A study measured BMD in 76 women and 22 men 2-3 years post-RYGB using dual X-ray densitometry.
- Results showed inverse correlation between BMD and age, and positive correlation with BMI and preoperative weight excess.
- Significant rates of osteopenia and osteoporosis were observed, particularly in older women and men, despite supplementation.
Impact:
- Findings highlight the persistent risk of osteopenia and osteoporosis after RYGB, irrespective of supplementation.
- Emphasizes the need for serial BMD measurements and individualized risk factor management in post-bariatric surgery patients.
- Informs clinical practice regarding long-term bone health monitoring and intervention strategies.
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