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A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Acute kidney injury in the elderly
1Division of Nephrology, University of Virginia Health System, Charlottesville, VA 22908, USA. MHR9R@hscmail.mcc.virginia.edu
Clinics in Geriatric Medicine
|July 16, 2013
Summary
Elderly patients are at high risk for acute kidney injury (AKI) due to age-related kidney changes and other factors. Individualized care and prevention are crucial for managing AKI in older adults.
Area of Science:
- Nephrology
- Geriatrics
- Internal Medicine
Background:
- Aging kidneys exhibit structural and functional changes, increasing susceptibility to acute kidney injury (AKI).
- Elderly individuals face compounded risks for AKI due to comorbidities, polypharmacy, and invasive procedures.
- AKI in older adults is linked to substantial morbidity and mortality.
Purpose of the Study:
- To highlight the increased vulnerability of elderly patients to acute kidney injury.
- To emphasize the factors contributing to AKI risk in the aging population.
- To advocate for individualized treatment and preventive strategies for AKI in the elderly.
Main Methods:
- Review of existing literature on aging kidney physiology and AKI pathophysiology.
- Analysis of risk factors associated with AKI in patients over 65.
- Discussion of clinical outcomes and management considerations for elderly AKI patients.
Main Results:
- Age-related kidney changes significantly predispose older adults to AKI.
- Comorbidities, polypharmacy, and procedures exacerbate AKI risk in the elderly.
- Despite increased risks, many elderly patients can recover from AKI with appropriate care.
Conclusions:
- AKI management in the elderly requires personalized decision-making, not solely based on age.
- Preventive measures are essential to mitigate the impact of AKI in older populations.
- Thoughtful, individualized care can lead to positive outcomes for elderly patients surviving AKI.
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