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Transplantation in the elderly patient

Douglas Scott Keith1

  • 1Department of Medicine, Division of Nephrology, University of Virginia Medical Center, Charlottesville, VA 22908-0133, USA. dsk9s@virginia.edu

Clinics in Geriatric Medicine
|July 16, 2013
PubMed

During the last 2 decades, the number of kidney transplants performed in the candidates older than 65 years has grown dramatically. For selected geriatric patients with end-stage kidney failure, kidney transplantation has emerged as a potential option for treatment of their end organ failure. Aging is associated with functional changes to the immune system known as immunosenescence, and this age-related decline in immune function has important implications for immunosuppression in this subgroup of kidney transplant recipients.

Keywords:
ElderlyImmunosenescenceImmunosuppressionKidney transplantationSelectionSurvival

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