Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Roxadustat in Kidney Transplant Recipients with ESA-Hyporesponsive Anemia: A Prospective Single-Center Cohort Study.

Life (Basel, Switzerland)·2026
Same author

Impella 5.5 Support in Severe Cardiogenic Shock: Outcomes From the First Spanish Multicentre Cohort in Heart Transplant Centres.

Interdisciplinary cardiovascular and thoracic surgery·2026
Same author

Envarsus Versus Advagraf in De Novo Kidney Transplant Recipients: A Comparative Pharmacokinetic Study.

Life (Basel, Switzerland)·2026
Same author

Erratum for Garcia et al., "Dual transcriptomic profiling of <i>Staphylococcus aureus</i> endocarditis in a porcine model reveals strong parallels with human infection".

mBio·2026
Same author

Serum proteomics mirrors the histopathological changes underlying different etiologies of primary mitral valve disease.

Bioscience reports·2025
Same author

Dual transcriptomic profiling of <i>Staphylococcus aureus</i> endocarditis in a porcine model reveals strong parallels with human infection.

mBio·2025

Related Experiment Video

Updated: May 9, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
08:50

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

[Asymptomatic severe aortic stenosis: a reopened debate].

Stefano Urso1, Rafael Sadaba2, Elena de la Cruz3

  • 1Servicio de Cirugía Cardíaca, Fundación Jiménez Díaz, Madrid, España.

Medicina Clinica
|July 16, 2013
PubMed
Summary

Degenerative aortic stenosis affects 2-7% of adults over 65. Early surgery may benefit asymptomatic patients with low stroke volume, challenging the view of a homogenous patient group.

Keywords:
Aortic stenosisAortic valveAortic valve replacementEstenosis aórticaReemplazo de válvula aórticaVálvula aórtica

More Related Videos

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

Related Experiment Videos

Last Updated: May 9, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
08:50

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

Area of Science:

  • Cardiology
  • Valvular Heart Disease

Context:

  • Degenerative aortic stenosis is a prevalent condition in older adults, affecting 2-7% of those over 65.
  • Severe aortic stenosis necessitates aortic valve replacement in symptomatic patients or those with reduced left ventricle ejection fraction (LVEF) <.50.
  • The optimal management strategy for asymptomatic severe aortic stenosis with preserved LVEF remains under investigation.

Purpose:

  • To review recent findings on asymptomatic severe aortic stenosis.
  • To highlight the significance of low left ventricle stroke volume in this patient subgroup.
  • To inform clinical decision-making regarding early surgical intervention.

Summary:

  • Approximately one-third of asymptomatic severe aortic stenosis patients with preserved LVEF exhibit low left ventricle stroke volume.
  • Low stroke volume in this population may be associated with adverse survival outcomes.
  • Aortic valve replacement is generally a low-risk procedure, supporting consideration for early intervention in select cases.

Impact:

  • Challenges the traditional view of asymptomatic severe aortic stenosis as a uniform condition.
  • Suggests that patient stratification based on hemodynamic parameters like stroke volume is crucial.
  • Supports the consideration of early surgical intervention for asymptomatic severe aortic stenosis patients with low stroke volume.