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Updated: May 9, 2026

Growing a Cystic Fibrosis-Relevant Polymicrobial Biofilm to Probe Community Phenotypes
Published on: April 19, 2024
Clonal diversity among Burkholderia cepacia complex isolates from cystic fibrosis patients in a reference unit
Laura Barrado1, M Teresa Martinez, Jennifer Villa
1Servicio de Microbiología Clínica, Hospital Universitario 12 de Octubre, Madrid, Spain.
Introduction:
The epidemiology of Burkholderia cepacia complex (Bcc) in cystic fibrosis (CF) is not widely known.
Methods:
All CF patients with Bcc between 2002 and 2011 were reviewed, and a molecular analysis of isolates was performed.
Results:
The prevalence of Bcc infection was 7.2% (18/250). Molecular analysis of 16 Bcc isolates showed 5 species (7 B. contaminans, 6 B. cepacia, 1 B. cenocepacia, 1 B. multivorans, and 1 B. stabilis) and 13 sequence types. There were no cases of cross-transmission.
Conclusion:
A high diversity of Bcc species was found in infected CF patients.
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