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Myofibroma of the tongue: a case suggesting autosomal dominant inheritance
Nobutaka Tajima1, Takeshi Shiraishi1, Seigo Ohba2
1Assistant Professor, Department of Regenerative Oral Surgery, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Abstract:
Myofibroma and myofibromatosis are rare, benign mesenchymal neoplasms composed of spindle-shaped contractile myoid cells and myofibroblasts, which generally develop in infancy or before the age of 2 years. At present, the precise etiology of this condition is unknown, with most cases reported as sporadic. However, some cases have suggested the possibility of a familial pattern of inheritance, with both dominant and -recessive patterns of inheritance have been reported. Presented here is a case of myofibroma associated with a family history of myofibromatosis, suggesting autosomal-dominant inheritance.
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