Association study of BDNF with completed suicide in the Japanese population
Woraphat Ratta-Apha1, Akitoyo Hishimoto, Masakuni Yoshida
1Department of Psychiatry, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
Psychiatry Research
|July 16, 2013
Abstract:
We explored the association between the brain-derived neurotrophic factor gene with suicide using 307 Japanese completed suicides, 380 healthy controls, and data from previously published samples. The meta-analyses of the valine with methionine in codon 66 (Val66Met) single nucleotide polymorphism (SNP) showed that the Met-allele tended to be associated with attempted suicide in Asian populations, but not with the completed suicide.
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