Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Somatosensory, Motor, and Association Cortex01:23

Somatosensory, Motor, and Association Cortex

The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at the...
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Somatosensation01:33

Somatosensation

The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
Spinal Cord: Information Processing01:10

Spinal Cord: Information Processing

The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
Sensory Perception: Organization of the Somatosensory System01:11

Sensory Perception: Organization of the Somatosensory System

The somatosensory system is the central and peripheral nervous system component that senses and processes touch, pressure, pain, temperature, and body position or proprioception. The process of sensation takes place at three levels:
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the stimulus...
Hierarchy of Motor Control01:18

Hierarchy of Motor Control

The hierarchy of motor control refers to the different levels of organization and processing involved in controlling movement in the body. These levels range from higher cortical areas involved in planning and decision-making to lower spinal cord reflexes that respond automatically to external stimuli.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bracket Coding: The Optimal Balance Between Temporal Integration and Segregation in Early Visual Processing.

bioRxiv : the preprint server for biology·2026
Same author

Biodegradable Intra-arterial Devices for Focal Drug Delivery to Targeted Organs.

bioRxiv : the preprint server for biology·2026
Same author

Sensory-to-motor transformations: From serial pipelines to dynamic, distributed processes.

Neuroscience and biobehavioral reviews·2026
Same author

Responsive neurostimulation in children, adolescents, and young Adults-Longitudinal effectiveness and safety.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026
Same author

Modulation of metastable ensemble dynamics explains the inverted-U relationship between tone discriminability and arousal in auditory cortex.

Neuron·2025
Same author

Orofacial Movements: Individuality and Stereotypy When Mice Move a Single Whisker to Touch.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2025
Same journal

Fast-conducting mechanonociceptors uniquely engage reflexive and affective pain circuitry to drive protective responses.

Neuron·2026
Same journal

Sparse component analysis: A method that uncovers separable computations within neural population activity.

Neuron·2026
Same journal

Spatiomolecular mapping reveals anatomical organization of heterogeneous cell types in the human nucleus accumbens.

Neuron·2026
Same journal

TGF-β1-induced endothelial transcytosis drives blood-brain barrier leakage during aging.

Neuron·2026
Same journal

Image space opens up for visual neuroscience.

Neuron·2026
Same journal

Septal GLP-1 receptors control alcohol taking and seeking.

Neuron·2026
See all related articles

Related Experiment Video

Updated: May 9, 2026

Combined Peripheral Nerve Stimulation and Controllable Pulse Parameter Transcranial Magnetic Stimulation to Probe Sensorimotor Control and Learning
14:47

Combined Peripheral Nerve Stimulation and Controllable Pulse Parameter Transcranial Magnetic Stimulation to Probe Sensorimotor Control and Learning

Published on: April 21, 2023

Motor cortex feedback influences sensory processing by modulating network state.

Edward Zagha1, Amanda E Casale, Robert N S Sachdev

  • 1Department of Neurobiology, Yale School of Medicine, New Haven, CT 06520, USA.

Neuron
|July 16, 2013
PubMed
Summary
This summary is machine-generated.

Motor cortex activity influences sensory processing by altering network states in the somatosensory cortex. This corticocortical communication enhances sensory discrimination during active exploration.

More Related Videos

Force and Position Control in Humans - The Role of Augmented Feedback
06:31

Force and Position Control in Humans - The Role of Augmented Feedback

Published on: June 19, 2016

Stimulating the Lip Motor Cortex with Transcranial Magnetic Stimulation
12:09

Stimulating the Lip Motor Cortex with Transcranial Magnetic Stimulation

Published on: June 14, 2014

Related Experiment Videos

Last Updated: May 9, 2026

Combined Peripheral Nerve Stimulation and Controllable Pulse Parameter Transcranial Magnetic Stimulation to Probe Sensorimotor Control and Learning
14:47

Combined Peripheral Nerve Stimulation and Controllable Pulse Parameter Transcranial Magnetic Stimulation to Probe Sensorimotor Control and Learning

Published on: April 21, 2023

Force and Position Control in Humans - The Role of Augmented Feedback
06:31

Force and Position Control in Humans - The Role of Augmented Feedback

Published on: June 19, 2016

Stimulating the Lip Motor Cortex with Transcranial Magnetic Stimulation
12:09

Stimulating the Lip Motor Cortex with Transcranial Magnetic Stimulation

Published on: June 14, 2014

Area of Science:

  • Neuroscience
  • Systems Neuroscience
  • Sensory Processing

Background:

  • Long-range corticocortical connections are crucial for context-dependent sensory processing.
  • The precise influence of these pathways on target regions remains largely unknown.

Purpose of the Study:

  • To investigate how primary motor cortex (M1) activity modulates primary somatosensory cortex (S1) network states.
  • To understand the role of corticocortical feedback in sensory coding and discrimination.

Main Methods:

  • Studied the mouse whisker system to examine M1-S1 interactions.
  • Utilized electrophysiological recordings to observe network state dynamics.
  • Performed experiments to identify the direct corticocortical feedback pathway.

Main Results:

  • M1 and S1 exhibit coherent, context-dependent network state changes.
  • M1 activity directly drives shifts in S1 network states.
  • The direct corticocortical feedback pathway provides precise modulation of network dynamics.
  • Activated network states enhance the reliability of sensory responses to complex stimuli.

Conclusions:

  • Corticocortical communication from M1 plays a vital role in modulating S1 network states.
  • This modulation significantly impacts sensory coding, improving sensory discrimination.
  • M1 influences S1 to prime it for enhanced sensory processing during active exploration.