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Harmonic Nanoparticles for Regenerative Research
Published on: May 1, 2014
Single KTP nanocrystals as second-harmonic generation biolabels in cortical neurons
Ludovic Mayer1, Abdallah Slablab, Géraldine Dantelle
1Laboratoire de Physique de la Matière Condensée-Ecole Polytechnique-CNRS, UMR 7643, 91128 Palaiseau Cedex, France.
Nanoscale
|July 16, 2013
Abstract:
We report an efficient colloidal synthesis of KTiOPO4 (KTP) nanocrystals with excellent crystallinity and the direct observation of optical second-harmonic generation (SHG) from discrete KTP nanocrystals in neurons cultured from mammalian brain cortex. Direct internalization and monitoring of these nanoparticles was successfully achieved without limitations from cytotoxicity, bleaching and blinking emission.
