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Related Experiment Video

Updated: May 9, 2026

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

High-Voltage CMOS Controller for Microfluidics.

M Khorasani, M Behnam, L van den Berg

    IEEE Transactions on Biomedical Circuits and Systems
    |July 16, 2013
    PubMed
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    A novel high-voltage microfluidic controller chip enables portable genetic analysis. This integrated circuit advances microfluidic technology for cost-efficient, high-performance applications.

    Area of Science:

    • Electrical Engineering
    • Biotechnology
    • Materials Science

    Background:

    • Microfluidic systems require precise high-voltage control for various applications.
    • Existing solutions can be bulky, expensive, or lack integration.

    Purpose of the Study:

    • To present a novel high-voltage microfluidic controller integrated circuit.
    • To enable a portable and cost-efficient platform for genetic analysis.

    Main Methods:

    • Designed a microfluidic controller using DALSA's 0.8-mum low-voltage/high-voltage complementary metal-oxide semiconductor/double diffused metal-oxide semiconductor process.
    • Integrated four high-voltage output drivers capable of switching 300 V.
    • Incorporated a dc-dc boost converter generating up to 68 V with external passive components.

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    Last Updated: May 9, 2026

    Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
    18:11

    Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

    Published on: October 1, 2007

    High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods
    07:51

    High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods

    Published on: December 23, 2013

    Generation of Dynamical Environmental Conditions using a High-Throughput Microfluidic Device
    14:48

    Generation of Dynamical Environmental Conditions using a High-Throughput Microfluidic Device

    Published on: April 17, 2021

    Main Results:

    • Successfully designed and demonstrated a high-voltage microfluidic controller chip.
    • The integrated circuit drivers can switch 300 V, and the boost converter generates 68 V.
    • The controller facilitates a portable and cost-efficient genetic analysis platform when combined with a CCD optical system and glass microfluidic channel.

    Conclusions:

    • The developed integrated circuit is an advancement in microfluidic technology.
    • This technology enables portable, cost-efficient platforms for genetic analysis.
    • The high-voltage controller offers significant potential for point-of-care diagnostics and research.