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Related Experiment Video

Updated: May 9, 2026

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
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Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

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Oxygen Releasing Biomaterials for Tissue Engineering.

Gulden Camci-Unal1, Neslihan Alemdar, Nasim Annabi

  • 1Center for Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA ; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.

Polymer International
|July 16, 2013
PubMed
Summary
This summary is machine-generated.

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Oxygen-releasing biomaterials are emerging strategies to overcome diffusion limitations in thick tissue engineering. This review covers reagents and fabrication methods for regenerative engineering applications.

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Regenerative Medicine

Background:

  • Increasing demand for thick, vascularized tissue engineered constructs.
  • Mass transport and diffusion limitations hinder engineered tissue development.
  • Oxygen-releasing biomaterials offer a novel solution.

Purpose of the Study:

  • To summarize oxygen-releasing reagents for regenerative engineering.
  • To review fabrication approaches for oxygen-releasing biomaterials.
  • To highlight applications in tissue engineering.

Main Methods:

  • Literature review of oxygen-releasing reagents.
  • Analysis of fabrication techniques for biomaterials (thin films, microparticles, 3D scaffolds).
  • Discussion of potential applications in regenerative engineering.
Keywords:
cell survivaloxygen-releasing biomaterialsperoxidestissue engineering

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Last Updated: May 9, 2026

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

Affordable Oxygen Microscopy-Assisted Biofabrication of Multicellular Spheroids
13:21

Affordable Oxygen Microscopy-Assisted Biofabrication of Multicellular Spheroids

Published on: April 6, 2022

Fabrication and Operation of an Oxygen Insert for Adherent Cellular Cultures
11:56

Fabrication and Operation of an Oxygen Insert for Adherent Cellular Cultures

Published on: January 6, 2010

Main Results:

  • Identified various oxygen-releasing reagents suitable for biomaterial integration.
  • Outlined diverse fabrication methods for oxygen-releasing biomaterials.
  • Highlighted the potential of these materials to address diffusion limitations.

Conclusions:

  • Oxygen-releasing biomaterials are promising for advancing tissue engineering.
  • Further research into reagents and fabrication is crucial for clinical translation.
  • These strategies can enable the creation of larger, more functional engineered tissues.