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[Abnormal lung uptake of 123I-BMIPP]
Shirou Ishii1, Koichi Sugimoto, Masayuki Miyajima
1Department of Radiology, Fukushima Medical University.
Kaku Igaku. the Japanese Journal of Nuclear Medicine
|July 17, 2013
Summary
Unusual lung uptake of 123I-BMIPP was observed during cardiac imaging in an 81-year-old male. This unexpected finding may be linked to aggregated radiotracer due to cold temperatures.
Area of Science:
- Nuclear Medicine
- Cardiology
- Radiopharmacology
Background:
- Cardiac scintigraphy is crucial for diagnosing heart conditions.
- 123I-BMIPP is a radiotracer used for myocardial imaging.
- Investigating unexpected findings during diagnostic procedures is essential.
Observation:
- An 81-year-old male presented with chest pressure, prompting cardiac investigation.
- Dual scintigraphy using 201Tl and 123I-BMIPP was performed.
- Multiple lung uptakes of 123I-BMIPP were detected, contrasting with 201Tl uptake.
Findings:
- Chest X-ray and CT scans revealed no corresponding pulmonary lesions.
- The observed lung accumulation of 123I-BMIPP is not previously reported.
- A potential cause identified is embolism from aggregated 123I-BMIPP due to cold exposure.
Implications:
- This case highlights a potential artifact in 123I-BMIPP scintigraphy.
- Understanding radiotracer behavior under different conditions is vital for accurate interpretation.
- Further investigation into cold-induced aggregation of 123I-BMIPP may be warranted.
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