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A link between two tumorigenic proteins, CD44 and p21WAF1: CD44 increases phorbol ester-induced expression of p21WAF1

Christina Lindner1, Pavel Urbánek, Birgit Pavelka

  • 1Leibniz Institute for Age Research - Fritz Lipmann Institute, Beutenbergstr. 11, 07745 Jena, Germany.

FEBS Letters
|July 17, 2013
PubMed

Keywords:
Agar colony formationCD44CD44KR-Mt and CD44KK-MtCHXERMERM proteinsEzFACSICDKDMAPKMEKPKCRNA and protein stabilizationRas/MAPK-pathwayTPAVcontrolctrlcycloheximidedeletion of extracellular domaindeletion of the intracellular domainempty vectorezrinezrin, radixin, moesinfluorescence activated cell sortingintracellular domainknockdownmitogen activated kinasemitogen activated protein kinasemutations of the ERM binding domain of CD44p21phorbol-12-myristate 13-acetateprotein kinase CqRT-PCRquantitative real-time PCRΔEΔICD

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