Single-dose oral lacosamide in refractory simple partial status epilepticus: case report and review
Maximiliano A Hawkes1, Marcos Fernández Suárez, Gabriela Ugarnes
1Neurology Department, Raúl Carrea Institute for Neurological Research (FLENI), Buenos Aires, Argentina. maxihawkes@icloud.com
Objectives:
This study aimed to present 2 patients with simple partial refractory status epilepticus (RSE) treated with a single oral lacosamide (LCM) dose and to review the literature on this topic.
Method:
A retrospective description of 2 patients with simple partial RSE treated with 300 mg of LCM per os (p.o.) and a literature review were done.
Results:
Both patients responded to single-dose oral LCM treatment with seizure cessation after 30 minutes.
Conclusions:
This is the first report on successful treatment of simple partial RSE with a single-dose of LCM p.o.. Oral LCM might represent an option for treatment of patients presenting with simple partial RSE.
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