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Published on: October 7, 2016
Boronic acid-containing hydrogels: synthesis and their applications
1State Key Laboratory of Medicinal Chemical Biology, The Co-Innovation Center of Chemistry and Chemical Engineering of Tianjin, Key Laboratory of Functional Polymer Materials, Institute of Polymer Chemistry, College of Chemistry, Nankai University, Tianjin 300071, China. yongjunzhang@nankai.edu.cn.
Chemical Society Reviews
|July 18, 2013
Summary
Boronic acid hydrogels offer glucose-sensitivity and self-healing for biomedical uses. This review covers their synthesis, properties, and applications in glucose sensors and insulin delivery systems.
Area of Science:
- Materials Science
- Biomedical Engineering
- Polymer Chemistry
Background:
- Boronic acid-containing hydrogels are advanced intelligent materials.
- These hydrogels possess unique properties like glucose-sensitivity, reversibility, and self-healing.
- They have significant applications, particularly in the biomedical field.
Purpose of the Study:
- To provide a comprehensive overview of boronic acid-containing hydrogels.
- To review their synthesis, properties, and diverse applications.
- To highlight recent advancements and future directions in this research area.
Main Methods:
- Review of existing literature on boronic acid hydrogels.
- Categorization of hydrogels into macroscopic, microgels, and self-assembled films.
- Analysis of applications focusing on glucose sensors and insulin delivery devices.
Main Results:
- Detailed examination of the synthesis and properties of various boronic acid hydrogels.
- Exploration of applications, emphasizing glucose-sensing and self-regulated insulin delivery.
- Identification of new developments and emerging trends in the field.
Conclusions:
- Boronic acid hydrogels are versatile materials with significant potential in biomedical applications.
- Further research is needed to address current challenges and explore new innovative directions.
- The field is rapidly evolving, with promising advancements in sensor and drug delivery technologies.

