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Infant Auditory Processing and Event-related Brain Oscillations
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A low-frequency oscillatory neural signal in humans encodes a developing decision variable.

Jan Kubanek1, Lawrence H Snyder, Bingni W Brunton

  • 1Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.

Neuroimage
|July 23, 2013
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Summary

Brain signals for hand movement decisions accumulate sensory evidence, similar to eye movement decisions in monkeys. This research reveals how the brain integrates information for action choices.

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Area of Science:

  • Neuroscience
  • Cognitive Science
  • Decision Science

Background:

  • Perceptual decisions integrate sensory evidence over time.
  • Neural mechanisms for evidence accumulation are studied in oculomotor systems for eye movements.
  • Analogous processes in the somatomotor system for hand movements are hypothesized.

Purpose of the Study:

  • Investigate neural correlates of decision-making using hand movements.
  • Determine if sensory evidence accumulation for hand movements mirrors eye movement systems.
  • Characterize the neural representation of decision variables in humans.

Main Methods:

  • Humans performed a decision task integrating discrete sensory evidence.
  • Decisions were signaled via hand or eye movements.
  • Low-frequency electrophysiological signals were recorded over centroparietal regions.

Main Results:

  • A specific electrophysiological signal in centroparietal regions encodes the decision variable for hand movements.
  • This signal ramps up proportionally to evidence, remains graded, and peaks before movement.
  • The signal shows properties of evidence accumulation, including encoding evidence polarity and temporal integration.

Conclusions:

  • The somatomotor system exhibits evidence accumulation for hand movement decisions, analogous to the oculomotor system for eye movements.
  • A specific low-frequency neural signal plays a key role in integrating sensory evidence for hand-based choices.
  • Basic neural principles of decision-making may be shared across different motor systems.