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Updated: May 9, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

Lessons from next-generation sequencing analysis in hematological malignancies.

E Braggio1, J B Egan, R Fonseca

  • 1Mayo Clinic in Arizona, 13400 East Shea Boulevard, Scottsdale, AZ, USA.

Blood Cancer Journal
|July 23, 2013
PubMed
Summary

Next-generation sequencing advances hematological malignancy research, improving diagnosis and treatment. This technology is transitioning to routine clinical use for personalized medicine strategies.

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Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.