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[A case of celiac disease]
Tae-Geun Gweon1, Chul-Hyun Lim, Seoug-Wook Byeon
1Department of Internal Medicine, The Catholic University College of Medicine, Seoul, Korea.
Summary
This report details the first diagnosed case of celiac disease in Korea, a gluten-induced small intestine disorder. The patient
Area of Science:
- Gastroenterology
- Immunology
- Internal Medicine
Background:
- Celiac disease, a chronic small intestine disorder triggered by gluten, affects 1% of Western populations but is rare in Asia.
- No prior cases of celiac disease have been documented in Korea, making this report significant.
Observation:
- A 36-year-old woman presented with abdominal pain, diarrhea, anemia, and osteoporosis.
- Endoscopic findings revealed duodenal micronodularity, while capsule endoscopy and enteroscopy demonstrated villous atrophy and blunting.
- Small intestinal biopsy confirmed villous atrophy with lymphocytic infiltration, characteristic of celiac disease.
Findings:
- The patient was diagnosed with celiac disease based on clinical presentation and histopathological findings.
- Following a gluten-free diet, the patient experienced significant improvement in symptoms including diarrhea, abdominal pain, anemia, and osteoporosis.
Implications:
- This case establishes the presence of celiac disease in Korea, challenging previous assumptions about its rarity in the region.
- It highlights the importance of considering celiac disease in patients with compatible symptoms, regardless of geographic location.
- The successful treatment outcome emphasizes the efficacy of a gluten-free diet in managing celiac disease.
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