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Updated: May 9, 2026

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
11:50

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

Published on: July 9, 2010

Ischemic mitral regurgitation

Jack H Boyd1

  • 1Division of Cardiothoracic Surgery, Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA. jhboyd@iupui.edu

Circulation Journal : Official Journal of the Japanese Circulation Society
|July 24, 2013
PubMed

Insights

Chronic ischemic mitral regurgitation (IMR) affects many coronary artery disease patients, worsening prognosis. This review clarifies surgical techniques for IMR, covering traditional and novel approaches for mitral valve repair or replacement.

Area of Science:

  • Cardiovascular Surgery
  • Interventional Cardiology
  • Cardiac Medicine

Background:

  • Chronic ischemic mitral regurgitation (IMR) is a significant complication in 10-20% of coronary artery disease patients.
  • IMR is linked to poorer outcomes post-myocardial infarction and revascularization.
  • Current surgical management often involves coronary artery bypass grafting with restrictive annuloplasty.

Purpose of the Study:

  • To elucidate the rationale behind surgical techniques for chronic ischemic mitral regurgitation.
  • To define IMR and trace the evolution of surgical repair and replacement strategies.
  • To explore emerging and novel surgical interventions for IMR.

Main Methods:

  • Review of existing literature on surgical management of IMR.
  • Analysis of traditional surgical approaches, including mitral valve repair and replacement.
  • Examination of novel and emerging techniques for addressing IMR.

Main Results:

  • Coronary artery bypass grafting with restrictive annuloplasty remains the standard surgical approach for IMR.
  • Various novel techniques have been employed with mixed success rates.
  • Understanding the evolution of surgical strategies is key to optimizing IMR treatment.

Conclusions:

  • Surgical intervention for IMR requires careful consideration of established and innovative techniques.
  • Further research into novel approaches may improve outcomes for patients with IMR.
  • Optimizing mitral valve function is crucial for improving prognosis in patients with ischemic heart disease.

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