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Updated: May 9, 2026

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds
Published on: February 23, 2024
[Research progress of mesenchymal stem cells in burn wound repair]
Yusen Huo1, Hongjie Duan, Lingying Liu
1Department of Burn & Plastic Surgery, the First Affiliated Hospital of Chinese PLA General Hospital, Beijing, 100037, PR China.
Objective:
To review the research progress of mesenchymal stem cells (MSCs) in burn wound repair.
Methods:
The recent literature about MSCs involved in burn wound repair and mechanism was extensively reviewed and analyzed.
Results:
MSCs have the capacity of self-renew, rapid proliferation, differentiation and paracrine, and promote burn wound repair through differentiating into a series of skin wound cells and regulating wound microenvironment.
Conclusion:
MSCs have great potentials in the burn field. However, the cell survival and outcome are also facing challenges from poor microenvironment of the burn wound.
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