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Two new non-glycosidic iridoids from Sambucus ebulus
Lamberto Tomassini1, Sebastiano Foddai, Antonio Ventrone
1a Dipartimento di Biologia Ambientale , Università "Sapienza" , P. le A. Moro 5, I-00185, Roma , Italy.
Natural Product Research
|July 25, 2013
Summary
Two novel Valeriana-type iridoids were identified in Sambucus ebulus. These non-glycosidic compounds, 7-O-acetylpatrinoside aglycone and 10-O-acetylpatrinoside aglycone, were isolated from the plant
Area of Science:
- Phytochemistry
- Natural Products Chemistry
- Botany
Background:
- Sambucus ebulus L. is a widespread European herbaceous plant.
- Non-glycosidic iridoids are a class of natural compounds with diverse biological activities.
- The chemical constituents of Sambucus ebulus are not fully characterized.
Purpose of the Study:
- To isolate and elucidate the structures of new compounds from Sambucus ebulus.
- To investigate the 'Valeriana-type' iridoid content of the plant's aerial parts.
Main Methods:
- Isolation of compounds from aerial parts (leaves and young branches) of Sambucus ebulus.
- Structure elucidation using spectroscopic techniques (e.g., NMR, MS).
Main Results:
- Two new 'Valeriana-type' non-glycosidic iridoids were successfully isolated.
- The structures were identified as 7-O-acetylpatrinoside aglycone (1) and 10-O-acetylpatrinoside aglycone (2).
Conclusions:
- The study expands the knowledge of iridoid diversity in the Sambucus genus.
- The identified compounds represent novel chemical entities within the 'Valeriana-type' iridoid class.