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Updated: May 9, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
[An initial study on the feasibility of diagnosing myocardial ischemia with CT first-pass myocardial perfusion
Qi Wang1, Jing Qin, Lu-yue Gai
1Department of Cardiology, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Objective:
To assess the feasibility and accuracy of CT first-pass myocardial perfusion imaging (CT first-pass MPI) at rest for diagnosis of myocardial ischemia. Results of adenosine-induced myocardial perfusion scintigraphy (MPS) were used as gold standard.
Methods:
Twenty-two patients with suspected or diagnosed coronary artery disease (CAD) were included and CT coronary angiography (CTCA) and MPS were performed within 2 weeks. CT first-pass MPI detected myocardial ischemia results through analyzing the raw date of CTCA were compared with MPS results.
Results:
The sensibility, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of CT first-pass MPI at rest for detecting myocardial ischemia were 92% (12/13), 78% (7/9), 86% (12/14), 88% (7/8) and 86% (19/22), respectively.
Conclusion:
CT first-pass MPI at rest could detect myocardial ischemia with an accuracy similar to that of MPS.
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