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Related Experiment Videos

Cerebral botryomycosis: case study.

C B Gillock1, K S Sahni, V R Mumaw

  • 1Department of Pathology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298-0433.

The Journal of Infectious Diseases
|September 1, 1990
PubMed
Summary
This summary is machine-generated.

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A brain abscess initially suspected as actinomycosis was diagnosed as botromycosis caused by Streptococcus sanguis. This case highlights differentiating botromycosis from actinomycosis in brain abscesses.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Microbiology

Background:

  • Brain abscesses can be challenging to diagnose, with actinomycosis being a common differential diagnosis.
  • Accurate identification of the causative pathogen is crucial for effective treatment.

Observation:

  • A 32-year-old male developed a brain abscess post-oral surgery.
  • Initial suspicion of actinomycosis based on clinical presentation and "sulfur granules" was not confirmed by anaerobic cultures.
  • Histological and electron microscopy findings, along with positive staining, pointed towards a coccoid organism.

Findings:

  • Aerobic cultures identified Streptococcus sanguis and Pseudomonas cepacia.
  • Histological and immunologic assays ruled out Actinomyces israelii.

Related Experiment Videos

  • Electron microscopy confirmed gram-positive cocci morphology, leading to a diagnosis of botromycosis due to S. sanguis.

    • Implications:

    • This case underscores the importance of considering botromycosis in the differential diagnosis of brain abscesses, particularly those mimicking actinomycosis.
    • It highlights the utility of integrated diagnostic methods, including histology, immunofluorescence, and electron microscopy, for identifying causative agents.
    • The association with intermittently treated jaw disease warrants further investigation.