Related Experiment Video
Updated: May 9, 2026

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
Renal denervation for arrhythmias: hope or hype?
Jonathan S Steinberg1, Evgeny Pokushalov, Suneet Mittal
1Arrhythmia Institute, Valley Health System, Columbia University College of Physicians & Surgeons, New York, NY, USA. jss7@columbia.edu
Abstract:
Renal artery denervation (RDN) has been introduced as an ablation procedure that can effectively treat drug-resistant forms of hypertension. The ablative lesions reduce the afferent and efferent sympathetic nerve traffic to and from the kidneys, thus improving blood pressure control. Because of better control of blood pressure, and because the procedure reduces central sympathetic output to sensitive structures within the cardiovascular system, it has been hypothesized that RDN may be a valuable antiarrhythmic intervention. Preliminary results using RDN for atrial fibrillation control are promising. This review focuses on the mechanisms by which RDN may function as an antiarrhythmic treatment and early clinical results.
Related Concept Videos
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Heart Failure Drugs: Diuretics
Antiarrhythmic Drugs: Class II Agents as β-Adrenergic Blockers
Heart Failure V: Medical Management
Dysrhythmias VI: Management of Dysrhythmias
Heart Failure Drugs: Inotropic Agents
