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Updated: May 9, 2026

A Proteoliposome-Based Efflux Assay to Determine Single-molecule Properties of Cl- Channels and Transporters
Published on: April 20, 2015
Fast transport of HCl across a hydrophobic layer over macroscopic distances by using a Pt(II) compound as the
Antonino Giannetto1, Santo Lanza, Fausto Puntoriero
1Dipartimento di Scienze Chimiche, Università di Messina, Via F. Stagno d'Alcontres 31, 98166 Messina, Italy.
Abstract:
[Pt(H-(ethyl)2-dithiooxamidate)2] plays the role of a HCl symporter, allowing fast HCl transport over macroscopic distances (cm scale) across a hydrophobic layer made of a chloroform solution, without any stirring. The process is limited by interfacial transfer, whereas HCl is transported within the hydrophobic phase at extremely high rates.
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