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Related Experiment Video

Updated: May 9, 2026

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits (Oryctolagus cuniculus)

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits (Oryctolagus cuniculus)

Published on: July 31, 2021

Preventing newborn infection with maternal immunization.

Steven Black¹, Immaculada Margarit, Rino Rappuoli

¹Center for Global Health, Cincinnati Children's Hospital, Cincinnati, OH 45229, USA.

Science Translational Medicine

|July 26, 2013

Summary

This summary is machine-generated.

Maternal immunization against Group B Streptococcus can protect newborns from sepsis. This strategy allows antibodies to transfer from mother to fetus, preventing fatal infections.

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Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic Poly(I:C)

Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic Poly(I:C)

Published on: March 25, 2016

Area of Science:

Obstetrics and Gynecology
Neonatal Medicine
Infectious Diseases

Background:

Group B Streptococcus (GBS) causes life-threatening sepsis in newborns.
Passive antibody transfer from mother to fetus is a key protective mechanism.

Purpose of the Study:

To discuss strategies for maternal immunization to prevent GBS disease.
To explore methods for protecting neonates from GBS infections.

Main Methods:

A scientific meeting was convened to discuss potential approaches.
Focus on maternal vaccination for passive antibody transfer.

Main Results:

Maternal immunization is a viable strategy for GBS prevention.
Antibodies generated in mothers can protect fetuses and newborns.

Conclusions:

Targeting pregnant women for GBS vaccination is crucial.
Maternal immunization offers a promising approach to reduce neonatal GBS disease.