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Presence of Gumprecht shadows (smudge cells) in bovine leukemia virus-positive cattle
Carlos Javier Panei1, Alejandra Larsen, Ester Teresa González
1Virology, Faculty of Veterinary Sciences, National University of La Plata, 60 and 118, CC 296, 1900 La Plata, Argentina; Immunology, Faculty of Veterinary Sciences, National University of La Plata, 60 and 118, CC 296, 1900 La Plata, Argentina; Member of CONICET (CCT-La Plata), Argentina.
Abstract:
Enzootic Bovine Leukosis is a chronic disease caused by the bovine leukemia virus (BLV). Smudge cells, also known as Gumprecht shadows, are not simple artifacts of slide preparation, but ragged lymphoid cells found mainly in peripheral blood smears from human patients with chronic lymphocytic leukemia. In this study, we report the presence of Gumprecht shadows in peripheral blood from BLV-positive cattle.
