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Updated: May 9, 2026
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Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
Intracerebral hematoma complicating herpes simplex encephalitis.
Aida Rodríguez-Sainz1, Inés Escalza-Cortina, Laura Guio-Carrión
1Department of Neurology, Hospital de Galdakao, Galdakao, Spain.
Clinical Neurology and Neurosurgery
|July 27, 2013
Summary
Intracranial hematomas can complicate herpes simplex encephalitis (HSE). Early suspicion and neuroimaging are crucial for timely diagnosis and treatment of this rare complication.
Area of Science:
- Neurology
- Infectious Diseases
- Neurosurgery
Background:
- Herpes simplex encephalitis (HSE) is a severe neurological condition.
- Intracranial hematoma is a rare but serious complication of HSE.
Observation:
- Two patients developed intracranial hematomas secondary to temporal lobe encephalitis caused by herpes simplex virus type 1.
- Hemorrhage occurred in the area of encephalitis, often presenting with overlapping symptoms.
- One patient required surgical evacuation of the hematoma.
Findings:
- A literature review identified 20 additional cases.
- Hemorrhage was present on admission in 35% of cases.
- Mortality was low (5.2%), with half of patients experiencing full recovery, though sequelae were common.
Implications:
- Intracranial bleeding in HSE, though infrequent, necessitates consideration for neurosurgical intervention.
- Worsening or persistent neurological symptoms, especially in the second week, warrant neuroimaging to rule out hemorrhage.
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