Related Experiment Video
Updated: May 9, 2026
12:04
The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice
Published on: November 1, 2015
2013 update: Hopkins lupus cohort
Monthida Fangtham1, Michelle Petri
1Division of Rheumatology, Johns Hopkins University School of Medicine, 1830 East Monument St Suite 7500, Baltimore, MD 21205, USA.
Current Rheumatology Reports
|July 27, 2013
Summary
This review highlights key findings from the Hopkins lupus cohort, focusing on systemic lupus erythematosus (SLE) treatments. Discover insights into prednisone, hydroxychloroquine, neurological issues, and steroid use for lupus flares.
Area of Science:
- Rheumatology
- Immunology
- Clinical Medicine
Background:
- The Hopkins lupus cohort is a significant longitudinal study tracking over 2,000 patients with systemic lupus erythematosus (SLE).
- Regular quarterly assessments provide rich data for clinical research.
Purpose of the Study:
- To review ten clinically significant studies derived from the Hopkins lupus cohort.
- To synthesize current understanding and treatment strategies for SLE.
Main Methods:
- Review of ten selected studies from the Hopkins lupus cohort.
- Analysis of data pertaining to cardiovascular events, treatment efficacy, and disease manifestations.
Main Results:
- Studies examined the role of prednisone in atherosclerosis and thrombosis.
- The preventive effects of hydroxychloroquine were investigated.
- Novel neurological manifestations of SLE were identified.
- Comparative analysis of steroid burst versus maintenance therapy for SLE flares was conducted.
Conclusions:
- Findings offer critical insights into managing SLE complications and optimizing treatment regimens.
- The review underscores the value of long-term cohort studies in advancing SLE patient care.
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